Premium
Hemolytic non‐uremic syndrome
Author(s) -
Chen Kenneth S.,
Neunert Cindy E.,
Crary Shelley E.,
Buchanan George R.
Publication year - 2011
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.23264
Subject(s) - medicine , microangiopathic hemolytic anemia , thrombotic thrombocytopenic purpura , atypical hemolytic uremic syndrome , hemolytic anemia , schistocyte , purpura (gastropod) , phenotype , immunology , platelet , gene , antibody , genetics , ecology , complement system , biology
We describe three children who developed isolated but severe microangiopathic hemolytic anemia without other manifestations of hemolytic uremic syndrome (HUS) or thrombotic thrombocytopenic purpura (TTP). All three recovered without specific treatment. We propose that they represent a unique phenotype in the spectrum of TTP and HUS, which we term “hemolytic non‐uremic syndrome.” Pediatr Blood Cancer 2012; 59: 167–169. © 2011 Wiley Periodicals, Inc.