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Clinical advances in hemophilia management
Author(s) -
Sharathkumar Anjali A.,
Carcao Manuel
Publication year - 2011
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.23193
Subject(s) - medicine , blood cancer , intensive care medicine , disease , disease management , cancer , pathology , parkinson's disease
Hemophilia is an excellent example in medicine where clinical translation of basic science discoveries has transformed the gloomy outlook of the disease. This review provides an overview of clinical advances in hemophilia management with a specific focus on the molecular heterogeneity of the disease and progress in management of patients with inhibitors. Novel therapeutics and the emerging ethical issues in the field of hemophilia are also discussed. Pediatr Blood Cancer 2011; 57: 910–920. © 2011 Wiley‐Liss, Inc.