Disseminated intravascular coagulation due to IgM‐mediated autoimmune hemolytic anemia | Zendy

Bleakly N. Teresa | Zendy; Fontaine Magali J. | Zendy; Pate Lisa L. | Zendy; Sutherland Scott M. | Zendy; Jeng Michael | Zendy

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Disseminated intravascular coagulation due to IgM‐mediated autoimmune hemolytic anemia

Author(s) -

Bleakly N. Teresa,

Fontaine Magali J.,

Pate Lisa L.,

Sutherland Scott M.,

Jeng Michael

Publication year - 2011

Publication title -

pediatric blood and cancer

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.116

H-Index - 105

eISSN - 1545-5017

pISSN - 1545-5009

DOI - 10.1002/pbc.23024

Subject(s) - medicine , hemolysis , autoimmune hemolytic anemia , disseminated intravascular coagulation , hemolytic anemia , gangrene , immunology , coagulation , cold agglutinin disease , cold agglutinin , anemia , pathology , antibody

Disseminated intravascular coagulation (DIC) due to red cell hemolysis has been previously attributed to transfusion‐related hemolytic reactions, but not to autoimmune hemolytic anemia. We report a case of DIC in a child with complement‐fixing IgM‐mediated cold‐agglutinin autoimmune hemolysis, which resulted in arterial thrombosis and gangrene of the upper and lower extremities. Pediatr Blood Cancer 2011; 57: 329–331. © 2011 Wiley‐Liss, Inc.

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