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Long‐term survival in a pediatric patient with supratentorial primitive neuro‐ectodermal tumor and extraneural metastasis at diagnosis
Author(s) -
Rubens Jeffrey,
Gosiengfiao Yasmin,
Tomita Tadanori,
Jacobsohn David A.,
Fangusaro Jason
Publication year - 2011
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.22995
Subject(s) - medicine , radiation therapy , blood cancer , chemotherapy , metastasis , surgical resection , pathology , central nervous system , cancer , radiology , surgery
Extraneural metastases of central nervous system (CNS) tumors are rare occurrences most commonly observed in medulloblastomas. Survival outcomes are generally dismal. Supratentorial primitive neuroectodermal tumors (stPNET) are rare childhood tumors with few documented cases of extraneural metastases. We present a rare occurrence of a 23‐month‐old patient with long‐term survival after diagnosis of stPNET with metastases to the lungs. This patient was treated with surgical resection, induction chemotherapy, tandem autologous hematopoietic cell rescues, and focal radiotherapy. We report long‐term survival for a patient with a stPNET and extraneural metastases at diagnosis following an intensive approach to treatment. Pediatr Blood Cancer 2011; 57: 341–344. © 2011 Wiley‐Liss, Inc.