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Hematopoietic cell transplantation with autologous cord blood in patients with severe aplastic anemia: An opportunity to revisit the controversy regarding cord blood banking for private use
Author(s) -
Rosenthal Joseph,
Woolfrey Ann E.,
Pawlowska Anna,
Thomas Sandra H.,
Appelbaum Frederick,
Forman Stephen
Publication year - 2011
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.22970
Subject(s) - medicine , cord blood , umbilical cord , aplastic anemia , malignancy , transplantation , haematopoiesis , hematopoietic cell , anemia , intensive care medicine , surgery , stem cell , immunology , bone marrow , biology , genetics
The controversy surrounding private banking of umbilical cord blood units (CBU), as a safeguard against future malignancy or other life‐threatening conditions, raises many questions in pediatric clinical practice. Recent favorable experiences with autologous transplantation for severe aplastic anemia using privately stored CBU, suggested a possible utility. While private banking is difficult to justify statistically or empirically, there may exist rare cases where autologous transplant of stored umbilical CBU could be beneficial. The reality of privately banked CBU and the possibility for future discovery of additional indications for autologous cord blood transplant, motivated us to re‐examine our attitudes towards private cord blood banking. Pediatr Blood Cancer 2011;56:1009–1012. © 2011 Wiley‐Liss, Inc.