Premium
Response of NF1‐related plexiform neurofibroma to High‐Dose Carboplatin
Author(s) -
Hummel Trent,
AnyaneYeboa Adjoa,
Mo Jun,
Towbin Alexander,
Weiss Brian
Publication year - 2011
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.22827
Subject(s) - medicine , carboplatin , plexiform neurofibroma , neurofibromatosis , seminoma , blood cancer , neurofibroma , oncology , pathology , radiology , chemotherapy , cancer , cisplatin
Plexiform neurofibromas (PN) are a hallmark of neurofibromatosis type 1 (NF1). These large nerve tumors can be disfiguring and surgery is the only known standard therapy. Surgical intervention may be suboptimal due to the diffuse nature of PN. Here, we present a case in which we describe the use of high‐dose carboplatin to treat the patient's testicular seminoma which resulted in the decrease in size of a PN in a patient with NF1. Pediatr Blood Cancer 2011;56:488–490. © 2010 Wiley‐Liss, Inc.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom