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PET imaging for pediatric oncology: An assessment of the evidence
Author(s) -
Portwine Carol,
Marriott Christopher,
Barr Ronald D.
Publication year - 2010
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.22747
Subject(s) - medicine , pediatric oncology , positron emission tomography , medical physics , blood cancer , clinical trial , scope (computer science) , pediatric cancer , clinical oncology , oncology , modality (human–computer interaction) , radiology , cancer , nuclear medicine , computer science , programming language , human–computer interaction
Positron emission tomography (PET) has shown potential benefits when used in therapeutic clinical trials for children with cancer. However, existing trials are limited in scope with small numbers of patients and varied observations, making accurate conclusions about the usefulness of PET scanning impossible. This review examines PET and its applications in pediatric oncology. While evidence is limited, there appears to be a basis for rigorous evaluation of this imaging modality before widespread application without validation from clinical trials. Pediatr Blood Cancer. 2010;55:1048–1061. © 2010 Wiley‐Liss, Inc.