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Haemolytic uraemic syndrome in a patient with acute lymphoblastic leukaemia
Author(s) -
Clarke Rachel T.,
Mitchell Chris
Publication year - 2010
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.22707
Subject(s) - medicine , blood cancer , pediatrics , lymphoblastic leukemia , neurological deficit , intensive care medicine , childhood cancer , cancer , surgery , leukemia
We describe a patient diagnosed with haemolytic uraemic syndrome (HUS) during long‐term maintenance therapy for childhood acute lymphoblastic leukaemia (ALL). He rapidly developed renal failure, hypertension and profound thrombocytopenia. Despite suffering a large intracerebral haemorrhage, he made a full recovery without residual neurological or renal deficit. His case raises the question of whether ALL or its treatments predispose an individual to developing HUS. Pediatr Blood Cancer. 2010;55:1402–1405. © 2010 Wiley‐Liss, Inc.