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Cystoscopy assisted transvesical biopsy of prostatic rhabdomyosarcoma
Author(s) -
England Richard J.,
AlAdnani Mudher,
Cohen Marta C.,
Godbole Prasad P.,
Marven Sean S.
Publication year - 2010
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.22600
Subject(s) - medicine , histology , cystoscopy , rhabdomyosarcoma , prostatectomy , biopsy , prostate , urology , histopathology , radiology , pathology , sarcoma , cancer , alternative medicine
Abstract The treatment of prostatic rhabdomyosarcoma (RMS) depends on tumour stratification based on site and histology. An increasing range of cytogenetic, molecular, and immunohistochemistry studies are required. This is difficult to achieve using standard cystoscopic biopsies alone. We present a 5‐year‐old male, diagnosed with a prostatic RMS. He underwent cystoscopy to confirm the diagnosis and at the same time tissue was obtained for histology using laparoscopic graspers via a STEP™ Port inserted percutaneously into the apex of his bladder. Histology and cytogenetics confirmed an embryonal botryoid RMS for which he received chemotherapy followed by a radical prostatectomy for residual disease. Pediatr Blood Cancer. 2010;55:583–586. © 2010 Wiley‐Liss, Inc.