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Retinal hemorrhages as a presenting sign in an adolescent patient with hepatosplenic gamma–delta T‐cell lymphoma
Author(s) -
Edwards Jeremy,
Simmons Elizabeth,
Cordero Steve,
Lieuw Kenneth,
Roberts Stephen
Publication year - 2010
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.22485
Subject(s) - medicine , organomegaly , lymphoma , bone marrow , anemia , t cell lymphoma , pathology , gamma delta t cell , t cell , immunology , polyneuropathy , t cell receptor , immune system
Hepatosplenic gamma–delta T‐cell lymphoma is a very rare, aggressive form of peripheral lymphoma first recognized in 1990. Patients often present with organomegaly, anemia, adenopathy, and B symptoms. Rarely in the literature is a pediatric patient described with this subtype of peripheral T‐cell lymphoma. Also, retinal hemorrhages have never been described as a presenting symptom of hepatosplenic gamma–delta T‐cell lymphoma. We describe an adolescent patient with hepatosplenic gamma–delta T‐cell lymphoma who presented with retinal hemorrhages, massive splenomegaly, bone marrow involvement, and B symptoms. Pediatr Blood Cancer 2010;55:190–192. © 2010 Wiley‐Liss, Inc.
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