Premium
Pseudometastasis secondary to histoplasmosis infection: False‐positive PET/CT findings
Author(s) -
Perko Ross,
Messinger Yoav,
Moertel Christopher
Publication year - 2010
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.22363
Subject(s) - histoplasmosis , medicine , itraconazole , positron emission tomography , medical diagnosis , biopsy , radiology , dermatology , antifungal
Positron emission computed tomography (PET)/CT is a common modality used in the workup of neoplastic conditions. However, false‐positive results may be produced by underlying infectious processes. We report two cases of false‐positive PET/CT studies secondary to histoplasmosis infections in both a pediatric and a young adult patient. After the diagnoses, one patient was observed with no therapy and the other received a complete course of itraconazole. In both cases biopsy results were positive for fungal elements consistent with histoplasmosis. Both patients were successfully managed and have had follow‐up histoplasmosis titers that reveal resolving infections. Pediatr Blood Cancer 2010;54:621–623. © 2009 Wiley‐Liss, Inc.