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A case of luteinizing thecoma with sclerosing peritonitis: Revisiting a link with anti‐epileptic drugs
Author(s) -
Nauen David W.,
Martin Allison,
Katz Aviva,
Cohen Debra,
Ranganathan Sarangarajan
Publication year - 2010
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.22325
Subject(s) - medicine , etiology , pathogenesis , dermatology , pathology
Luteinizing thecoma with sclerosing peritonitis (LTSP) is a rare ovarian tumor of unclear etiology and pathogenesis. The diagnostic entity was proposed in 1994, but a number of earlier reports described possible cases, and some suggested an association with anti‐epileptic drugs (AEDs). In presenting a new case we review the literature of previous cases to evaluate the possibility of such a link. When cases in reproductively immature patients are considered, evidence for an association between LTSP and AEDs is strongly suggested despite the rarity of the condition. Pediatr Blood Cancer 2010;54:470–472. © 2009 Wiley‐Liss, Inc.