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Conidiobolomycosis in relapsed acute lymphoblastic leukemia
Author(s) -
Radhakrishnan Nita,
Sachdeva Anupam,
Oberoi Jaswinder,
Yadav Satya Prakash
Publication year - 2009
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.22259
Subject(s) - medicine , lymphoblastic leukemia , blood cancer , zygomycosis , leukemia , isolation (microbiology) , cancer , antifungal , epidemiology , respiratory tract , protozoan infection , immunology , intensive care medicine , dermatology , amphotericin b , pathology , respiratory system , microbiology and biotechnology , biology
Invasive fungal infections in immunocompromised children suffering from hematological malignancies have been a major cause of morbidity and mortality. In recent years fungi other than aspergillus and candida are gaining importance. These emerging fungal infections have distinct epidemiological features and management issues especially in immunocompromised patients. Here we report the isolation of Conidiobolus coronatus , a rarely reported zygomycetes infection in a patient suffering from acute lymphoblastic leukemia. Conidiobolus generally causes indolent infection in the sino‐respiratory tract. They are known to be angioinvasive and can disseminate. There is no consensus regarding appropriate antifungal treatment for Conidiobolus infection. Pediatr Blood Cancer 2009; 53:1321–1323. © 2009 Wiley‐Liss, Inc.