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Improvement of diencephalic syndrome after partial surgery of optic chiasm glioma
Author(s) -
MarecBerard Perrine,
Szathmari Alexandru,
Conter Cécile,
Mottolese Carmine,
Berlier Pascale,
Frappaz Didier
Publication year - 2009
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.22085
Subject(s) - medicine , pilocytic astrocytoma , pathological , optic chiasm , biopsy , optic chiasma , cachexia , surgery , radiation therapy , enteral administration , endocrine system , chemotherapy , radiology , astrocytoma , glioma , cancer , parenteral nutrition , pathology , anatomy , cancer research , optic nerve , hormone
A 10‐month‐old male presented with sudden growth failure and cachexia. MRI showed a chiasma of the hypothalamic mass. Biopsy was avoided due to operative risks. Three cycles of chemotherapy were given, resulting in stable disease on MRI, but growth failure despite attempts at enteral feeding. Surgical biopsy was then performed. A 30% tumor reduction was observed on post‐operative imaging. Pathological examination revealed a pilocytic astrocytoma. After surgery, the child gained weight and his growth curve returned to normal. Enteral feeding was discontinued. After 4‐year of follow‐up, neurological development remains normal, with no residual or endocrine abnormalities. Pediatr Blood Cancer 2009;53:502–504. © 2009 Wiley‐Liss, Inc.