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Relationships among bleeding severity, health‐related quality of life, and platelet count in children with immune thrombocytopenic purpura
Author(s) -
Neunert Cindy E.,
Buchanan George R.,
Blanchette Victor,
Barnard Dorothy,
Young Nancy L.,
Curtis Christine,
Klaassen Robert J.
Publication year - 2009
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.21978
Subject(s) - medicine , thrombocytopenic purpura , immune thrombocytopenia , platelet , quality of life (healthcare) , purpura (gastropod) , health related quality of life , immune system , blood cancer , pediatrics , immunology , cancer , disease , ecology , nursing , biology
Important outcomes for children with immune thrombocytopenic purpura (ITP) include health‐related quality of life (HRQOL) and bleeding severity. A HRQOL instrument for children with ITP, the Kids' ITP Tools (KIT), was recently validated. Secondary analysis of the KIT database was performed to determine relationships among platelet count, bleeding severity and HRQOL. Bleeding severity grade correlated with platelet count in chronic ITP but not in acute ITP. Platelet count and bleeding severity failed to have any statistically significant correlations with the KIT scores. These findings suggest that relationships among outcome measures in children with ITP, using currently available instruments, remain poorly defined. Pediatr Blood Cancer 2009;53:652–654. © 2009 Wiley‐Liss, Inc.