Cerebral sinus thrombosis in a child with active ulcerative colitis and factor V Leiden | Zendy

Robison Nathan J. | Zendy; Dawlabani Nickolas | Zendy; Lastra Carlos R. | Zendy; Dhall Girish | Zendy

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Cerebral sinus thrombosis in a child with active ulcerative colitis and factor V Leiden

Author(s) -

Robison Nathan J.,

Dawlabani Nickolas,

Lastra Carlos R.,

Dhall Girish

Publication year - 2009

Publication title -

pediatric blood and cancer

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.116

H-Index - 105

eISSN - 1545-5017

pISSN - 1545-5009

DOI - 10.1002/pbc.21967

Subject(s) - medicine , exacerbation , ulcerative colitis , thrombosis , venous thrombosis , gastroenterology , cerebral venous sinus thrombosis , factor v leiden , surgery , disease

Ulcerative colitis (UC) is a rare cause of cerebral sinus thrombosis. We describe a 10‐year‐old patient with UC who developed cerebral sinus thrombosis during an acute exacerbation of his colitis and was found to be heterozygous for factor V Leiden. He was successfully treated with enoxaparin. Enoxaparin was then used for prophylaxis during acute exacerbations of his UC without any recurrence/progression of cerebral venous thrombosis. This report describes a cerebral thrombotic event in a child with UC and factor V Leiden. Pediatr Blood Cancer 2009;52:867–869. © 2009 Wiley‐Liss, Inc.

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