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Cerebral sinus thrombosis in a child with active ulcerative colitis and factor V Leiden
Author(s) -
Robison Nathan J.,
Dawlabani Nickolas,
Lastra Carlos R.,
Dhall Girish
Publication year - 2009
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.21967
Subject(s) - medicine , exacerbation , ulcerative colitis , thrombosis , venous thrombosis , gastroenterology , cerebral venous sinus thrombosis , factor v leiden , surgery , disease
Abstract Ulcerative colitis (UC) is a rare cause of cerebral sinus thrombosis. We describe a 10‐year‐old patient with UC who developed cerebral sinus thrombosis during an acute exacerbation of his colitis and was found to be heterozygous for factor V Leiden. He was successfully treated with enoxaparin. Enoxaparin was then used for prophylaxis during acute exacerbations of his UC without any recurrence/progression of cerebral venous thrombosis. This report describes a cerebral thrombotic event in a child with UC and factor V Leiden. Pediatr Blood Cancer 2009;52:867–869. © 2009 Wiley‐Liss, Inc.