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Congenital Rosai–Dorfman disease presenting with anemia, thrombocytopenia, and hepatomegaly
Author(s) -
Chow C.P.,
Ho H.K.,
Chan G.C.F.,
Cheung A.N.,
Ha S.Y.
Publication year - 2009
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.21880
Subject(s) - medicine , rosai–dorfman disease , blood cancer , cervical lymphadenopathy , anemia , presentation (obstetrics) , histiocytosis , disease , langerhans cell histiocytosis , dermatology , pathology , cancer , surgery
Rosai–Dorfman disease (RDD) is a rare entity of non‐Langerhans cell histiocytoses (non‐LCH) which usually presents with bilateral painless cervical lymphadenopathy. We describe a neonate with RDD who presented with anemia, thrombocytopenia and hepatomegaly. He recovered spontaneously with conservative management. This represents an atypical presentation of RDD. Conservative management with close monitoring can be adopted for some with systemic involvement. Pediatr Blood Cancer 2009;52:415–417. © 2008 Wiley‐Liss, Inc.