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Intracranial hemorrhage in childhood immune thrombocytopenic purpura
Author(s) -
Choudhary Dharma R.,
Naithani Rahul,
Mahapatra M.,
Kumar Rajat,
Mishra Pravas,
Saxena Renu
Publication year - 2009
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.21728
Subject(s) - medicine , thrombocytopenic purpura , presentation (obstetrics) , platelet , pediatrics , purpura (gastropod) , immune thrombocytopenia , intracerebral hemorrhage , intracranial haemorrhage , surgery , neurosurgery , subarachnoid hemorrhage , ecology , biology
We retrospectively analyzed 750 patients with ITP for development of intracranial hemorrhage (ICH). Seventeen cases with age range of 10 months to 18 years were studied. Ten patients were of acute ITP and seven had chronic ITP. Nine patients developed ICH one month after the onset of ITP and five patients had ICH on presentation. ICH was precipitated by trauma in four patients and possibly the use of NSAIDs in one patient. Median platelets counts at the time of ICH were 12 × 10 9 /L (range 2–50 × 10 9 /L). Most patients were treated with corticosteroids. Four patients (24%) died due to ICH. Pediatr Blood Cancer 2009;52:529–531. © 2008 Wiley‐Liss, Inc.