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Advanced small cell carcinoma of the ovary in a seventeen‐year‐old female, successfully treated with surgery and multi‐agent chemotherapy
Author(s) -
Kanwar Vikramjit S.,
Heath Jessica,
Krasner Carolyn N.,
Pearce Jennifer M.
Publication year - 2008
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.21333
Subject(s) - medicine , chemotherapy , blood cancer , ovary , surgery , imatinib , disease , thalidomide , ovarian carcinoma , ovarian cancer , cancer , oncology , multiple myeloma , myeloid leukemia
Advanced small cell carcinoma of the ovary (FIGO stage III or IV) is a rare and usually lethal tumor seen in adolescents and young women. In pediatric patients with advanced disease, there have been only two case reports of successful therapy, we report a third patient, diagnosed at 17 years of age, with an abdominal mass and metastatic disease to regional and distant lymph nodes, who was successfully treated with surgery and intensive multi‐agent chemotherapy. Imatinib, thalidomide, and celecoxib were also administered for up to 24 months following initial chemotherapy. She remains in remission 3 years from diagnosis. Pediatr Blood Cancer 2008;50:1060–1062. © 2007 Wiley‐Liss, Inc.