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Bacterial meningitis from Rothia mucilaginosa in patients with malignancy or undergoing hematopoietic stem cell transplantation
Author(s) -
Lee Alisa B.,
HarkerMurray Paul,
Ferrieri Patricia,
Schleiss Mark R.,
Tolar Jakub
Publication year - 2008
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.21286
Subject(s) - medicine , hematopoietic stem cell transplantation , malignancy , transplantation , bacterial meningitis , meningitis , stem cell , microbiology and biotechnology , surgery , genetics , biology
Opportunistic infections contribute to morbidity and mortality of patients undergoing hematopoietic stem cell transplantation and treatment for malignancies. Rothia mucilaginosa, a gram‐positive bacterium, is responsible for rare, but often fatal meningitis in severely immunocompromised patients. We describe two cases of meningitis from discrete strains of R. mucilaginosa on our pediatric bone marrow transplant unit, summarize the published cases of R. mucilaginosa meningitis in oncology and stem cell transplant patients, and provide updated recommendations regarding the use of antibiotic therapy in this patient population. Pediatr Blood Cancer 2008;50:673–676. © 2007 Wiley‐Liss, Inc.