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Laparoscopic versus open abdominal surgery in children with sickle cell disease is associated with a shorter hospital stay
Author(s) -
Goers Trudie,
Panepinto Julie,
DeBaun Michael,
Blinder Morey,
Foglia Robert,
Oldham Keith T.,
Field Joshua J.
Publication year - 2008
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.21245
Subject(s) - medicine , laparoscopy , surgery , abdominal pain , acute chest syndrome , complication , abdominal surgery , splenectomy , open surgery , laparoscopic surgery , blood transfusion , general surgery , disease , sickle cell anemia , spleen
Abstract Background Limited information exists comparing the post‐operative complication rate of laparoscopic or open abdominal surgeries in children with sickle cell disease (SCD). The primary objective of this study was to compare the outcomes in children with SCD who required laparoscopic or open abdominal surgery for a cholecystectomy or splenectomy. Procedure We conducted a retrospective analysis of laparoscopic and open abdominal surgeries performed in children with SCD (ages 0–20 years) at two medical centers from 1984 to 2004. The primary outcome measures were the rates of post‐operative pain and acute chest syndrome (ACS) episodes following laparoscopic or open abdominal surgery. The secondary outcome was length of hospital stay following surgery. We also examined the potential contribution of pre‐operative (transfusion) and intra‐operative factors (operating time, estimated blood loss, and end‐operative temperature) to post‐operative SCD‐related complications. Results A total of 140 cases were identified, 98 laparoscopic and 42 open. Episodes of post‐operative pain and ACS episodes were comparable between laparoscopic and open procedures (pain: 4% vs. 3%, P = 0.619; ACS: 5% vs. 5%, P = 0.933). Additionally, laparoscopic surgeries were associated with a significantly shorter hospital stay (2.9 vs. 5.4 days, 95% CI −3.7 to −1.4, P < 0.001). There was no difference in the number of hospital readmissions within 1 month of the surgery. Conclusions For children with SCD who need a cholecystectomy or splenectomy, laparoscopy is the preferred strategy because of a shorter hospital stay with a similar complication rate compared to open surgeries. Pediatr Blood Cancer 2008;50:603–606. © 2007 Wiley‐Liss, Inc.