Graft versus leukemia effect against juvenile myelomonocytic leukemia after unrelated cord blood transplantation | Zendy

Tanoshima Reo | Zendy; Goto Hiroaki | Zendy; Yanagimachi Masakatsu | Zendy; Kajiwara Ryosuke | Zendy; Kuroki Fumiko | Zendy; Yokota Shumpei | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

Graft versus leukemia effect against juvenile myelomonocytic leukemia after unrelated cord blood transplantation

Author(s) -

Tanoshima Reo,

Goto Hiroaki,

Yanagimachi Masakatsu,

Kajiwara Ryosuke,

Kuroki Fumiko,

Yokota Shumpei

Publication year - 2008

Publication title -

pediatric blood and cancer

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.116

H-Index - 105

eISSN - 1545-5017

pISSN - 1545-5009

DOI - 10.1002/pbc.21200

Subject(s) - juvenile myelomonocytic leukemia , medicine , leukemia , cord blood , transplantation , regimen , blood cancer , concordance , juvenile , oncology , complete remission , conditioning regimen , disease , gastroenterology , chemotherapy , surgery , immunology , cancer , hematopoietic stem cell transplantation , stem cell , haematopoiesis , genetics , biology

A 13‐month‐old female underwent unrelated cord blood transplantation (CBT) for juvenile myelomonocytic leukemia (JMML). In spite of progression of the disease after a conditioning regimen with high‐dose chemotherapy, a complete remission was induced in concordance with development of acute GVHD after reduction of the immunosupressant. She has been in complete remission for 1 year after transplantation. This case illustrates that CBT can provide a potent graft versus leukemia (GVL) effect against JMML. Pediatr Blood Cancer 2008;50:665–667. © 2007 Wiley‐Liss, Inc.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research