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Sudden onset blindness in sickle cell disease due to retinal artery occlusion
Author(s) -
Liem Robert I.,
Calamaras Diane M.,
Chhabra Manpreet S.,
Files Beatrice,
Minniti Caterina P.,
Thompson Alexis A.
Publication year - 2008
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.21152
Subject(s) - medicine , central retinal artery occlusion , disease , complication , retinal artery occlusion , retinopathy , presentation (obstetrics) , blindness , pathogenesis , occlusion , pediatrics , ophthalmology , retinal , cardiology , surgery , optometry , diabetes mellitus , endocrinology
Central retinal artery occlusion (CRAO) is a rare and potentially devastating cause of acute blindness in sickle cell disease (SCD) that is unique compared to classic sickle retinopathy. Few details related to this complication in SCD are known, including its risk factors, pathogenesis, presentation, treatment and outcomes. We present three patients with SCD and retinal artery occlusion. The overall variability in clinical presentation, treatment and prognosis reported in the literature underscores the need for a greater understanding of these factors as they relate to this complication in SCD. Pediatr Blood Cancer 2008;50:624–627. © 2007 Wiley‐Liss, Inc.