Hypocalcemia as a presentation for multifocal osteosarcoma | Zendy

Soltani Akbar | Zendy; HasaniRanjbar Shirin | Zendy; Moayyeri Alireza | Zendy

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Hypocalcemia as a presentation for multifocal osteosarcoma

Author(s) -

Soltani Akbar,

HasaniRanjbar Shirin,

Moayyeri Alireza

Publication year - 2008

Publication title -

pediatric blood and cancer

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.116

H-Index - 105

eISSN - 1545-5017

pISSN - 1545-5009

DOI - 10.1002/pbc.21102

Subject(s) - medicine , presentation (obstetrics) , osteosarcoma , biopsy , bone pain , hip pain , chemotherapy , case presentation , disease , insufficiency fracture , radiology , pathology , surgery , osteoporosis

We report the case of a 16‐year‐old male with multifocal osteosarcoma presented with symptomatic hypocalcemia. The patient presented signs of hypocalcemia accompanied by generalized bone pain and a femoral mass. Further evaluation revealed secondary hyperparathyroidism, highly elevated alkaline phosphatase levels, and generalized sclerotic and lytic lesions. Biopsy confirmed osteosarcomatosis. Despite aggressive chemotherapy, he died from progressive disease 2 months after diagnosis. The course of disease in this patient suggests that hypocalcemia reflects a poor prognosis. Pediatr Blood Cancer 2008;50:687–689. © 2007 Wiley‐Liss, Inc.

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