Low daytime pulse oximetry reading is associated with nocturnal desaturation and obstructive sleep apnea in children with sickle cell anemia | Zendy

Spivey John F. | Zendy; Uong Elizabeth C. | Zendy; Strunk Robert | Zendy; Boslaugh Sarah E. | Zendy; DeBaun Michael R. | Zendy

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Low daytime pulse oximetry reading is associated with nocturnal desaturation and obstructive sleep apnea in children with sickle cell anemia

Author(s) -

Spivey John F.,

Uong Elizabeth C.,

Strunk Robert,

Boslaugh Sarah E.,

DeBaun Michael R.

Publication year - 2008

Publication title -

pediatric blood and cancer

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.116

H-Index - 105

eISSN - 1545-5017

pISSN - 1545-5009

DOI - 10.1002/pbc.21054

Subject(s) - medicine , polysomnogram , obstructive sleep apnea , nocturnal , pulse oximetry , daytime , oxygen saturation , apnea , anemia , anesthesia , pediatrics , polysomnography , oxygen , chemistry , organic chemistry , atmospheric sciences , geology

A retrospective medical record review was established to test the hypothesis that in children with sickle cell anemia (SCA), a daytime oxygen saturation (SpO 2 ) ≤94% is associated with nocturnal desaturation with or without obstructive sleep apnea (OSA). Twenty children had a resting SpO 2 ≤94% and an abnormal polysomnogram (PSG). Seven patients had OSA and thirteen patients had nocturnal desaturation. The average daytime SpO 2 correlated with the average nighttime SpO 2 (Spearman correlation coefficient = 0.453; P = 0.045). Our results indicate that in children with SCA, a daytime SpO 2 ≤94% is a reasonable threshold to recommend a pulmonary evaluation, including a PSG. Pediatr Blood Cancer 2008;50:359–362. © 2006 Wiley‐Liss, Inc.

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