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Low daytime pulse oximetry reading is associated with nocturnal desaturation and obstructive sleep apnea in children with sickle cell anemia
Author(s) -
Spivey John F.,
Uong Elizabeth C.,
Strunk Robert,
Boslaugh Sarah E.,
DeBaun Michael R.
Publication year - 2008
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.21054
Subject(s) - medicine , polysomnogram , obstructive sleep apnea , nocturnal , pulse oximetry , daytime , oxygen saturation , apnea , anemia , anesthesia , pediatrics , polysomnography , oxygen , chemistry , organic chemistry , atmospheric sciences , geology
A retrospective medical record review was established to test the hypothesis that in children with sickle cell anemia (SCA), a daytime oxygen saturation (SpO 2 ) ≤94% is associated with nocturnal desaturation with or without obstructive sleep apnea (OSA). Twenty children had a resting SpO 2 ≤94% and an abnormal polysomnogram (PSG). Seven patients had OSA and thirteen patients had nocturnal desaturation. The average daytime SpO 2 correlated with the average nighttime SpO 2 (Spearman correlation coefficient = 0.453; P = 0.045). Our results indicate that in children with SCA, a daytime SpO 2 ≤94% is a reasonable threshold to recommend a pulmonary evaluation, including a PSG. Pediatr Blood Cancer 2008;50:359–362. © 2006 Wiley‐Liss, Inc.