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Parotid acinic cell carcinoma in a long‐term survivor of childhood acute lymphoblastic leukemia
Author(s) -
Cheuk Daniel Ka Leung,
Shek Tony Wai Hung,
Chan Godfrey Chi Fung,
Lau Yu Lung,
Ha Shau Yin,
Chiang Alan Kwok Shing
Publication year - 2008
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.21002
Subject(s) - medicine , acinic cell carcinoma , mucoepidermoid carcinoma , malignancy , pathological , parotid gland , cancer , salivary gland , oncology , lymphoblastic leukemia , leukemia , pathology
Secondary malignancies are an important cause of morbidity and mortality in childhood cancer survivors. Salivary gland tumors account for about 6% of the second cancers. The majority of these are mucoepidermoid carcinomas (MEC) of the parotid gland. We report the clinical and pathological features of a rarer histological type, acinic cell carcinoma (ACC), in a childhood acute lymphoblastic leukemia (ALL) survivor. The behavior of secondary ACC appears similar to primary tumor and similar treatment may be adopted. Early recognition and complete resection is important for achieving a good outcome. Careful monitoring for recurrence or a third malignancy is needed. Pediatr Blood Cancer 2008;50:636–639. © 2006 Wiley‐Liss, Inc.