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Idiopathic thrombocytopenic purpura: A 15‐year natural history study at the Children's Hospital Rijeka, Croatia
Author(s) -
Roganovic Jelena,
LeticaCrepulja Marina
Publication year - 2006
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.20995
Subject(s) - medicine , thrombocytopenic purpura , pediatrics , presentation (obstetrics) , purpura (gastropod) , natural history , platelet , immunology , surgery , ecology , biology
We review a 15‐year experience with childhood idiopathic thrombocytopenic purpura (ITP) at a tertiary‐care pediatric hospital in Croatia. Data confirm that ITP is typically a self‐limited bleeding disorder that usually presents with mild symptoms in children between 1 and 10 years of age and affects both sexes equally. At presentation, more than half of the children had platelet counts of <10 × 10 9 /L. The absence of preceding viral infection and insidious onset of symptoms were significantly associated with development of chronic ITP. In our experience, observation without specific therapy seems to be the optimal approach to a child with ITP. Pediatr Blood Cancer 2006;47:662–664. © 2006 Wiley‐Liss, Inc.