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Studies of chronic ITP in children and adolescents
Author(s) -
Nilsson Cecilia,
Tedgård Ulf,
Ljung Rolf
Publication year - 2006
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.20971
Subject(s) - medicine , platelet , desmopressin , subgroup analysis , antibody , immunology , pediatrics , meta analysis
This paper presents an ongoing study of children with chronic ITP in Sweden that addresses four specific questions: is there a subgroup of children with chronic ITP that have impaired platelet function? Do children in this subgroup have antibodies directed against surface glycoproteins that are crucial for platelet function? Can desmopressin improve the impaired platelet function in this subgroup? Do children with chronic ITP show signs of cell‐mediated cytotoxicity? Pediatr Blood Cancer 2006;47:660–661. © 2006 Wiley‐Liss, Inc.