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Late effects risk profiles using the long‐term follow‐up guidelines in Identical Twin Survivors of Acute Lymphoblastic Leukemia 1
Author(s) -
Howell Della L.,
Lew Glen,
Comeaux Laura G.,
Meacham Lillian R.
Publication year - 2007
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.20835
Subject(s) - medicine , cog , lymphoblastic leukemia , pediatrics , leukemia , oncology , intensive care medicine , artificial intelligence , computer science
As the number of pediatric cancer survivors increases, the cost of cure (i.e., late effects) needs to be measured through a consistent mechanism. Through the use of the Children's Oncology Group's (COG) Long‐Term Follow‐Up (LTFU) guidelines, individualized risk profiles can be discerned for each off‐therapy patient. These guidelines were used to compare and contrast risk profiles for identical twin females treated for acute lymphoblastic leukemia (ALL). The first twin was treated for high‐risk leukemia and the second for standard‐risk leukemia, each with different ALL protocols. Timely use of the LTFU guidelines has aided in identifying and treating their adverse late effects. Pediatr Blood Cancer 2007;49:349–352. © 2006 Wiley‐Liss, Inc.