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Hematometrocolpos in an adolescent female treated for pelvic Ewing sarcoma
Author(s) -
Gaillard Pamela,
Krasin Matthew J.,
Laningham Fred H.,
Hoffer Fredric A.,
Davidoff Andrew M.,
Spunt Sheri L.,
Smiley Linda,
Skapek Stephen X.
Publication year - 2008
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.20833
Subject(s) - medicine , sarcoma , radiation therapy , ewing's sarcoma , psychological intervention , presentation (obstetrics) , chemotherapy , radiology , radiography , pediatrics , surgery , pathology , nursing
Radiation therapy is often used to achieve local control of pelvic Ewing sarcoma in children. The effects of radiation on the female reproductive tract have been well documented in adults with gynecological malignancies, but the long‐term consequences of pelvic radiation in pre‐pubertal or adolescent girls are not as well described. We report a case of hematometrocolpos developing in an adolescent previously treated with chemotherapy and radiation therapy for pelvic Ewing sarcoma. We describe the clinical presentation, radiographic features, gross pathology, treatment strategies, outcome, as well as putative predisposing factors and preventative interventions. Pediatr Blood Cancer 2008;50:157–160. © 2006 Wiley‐Liss, Inc.