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Ewing sarcoma/primitive neuroectodermal tumor of the kidney in a child
Author(s) -
Maeda Miho,
Tsuda Akio,
Yamanishi Shingo,
Uchikoba Yoko,
Fukunaga Yoshitaka,
Okita Hajime,
Hata Junichi
Publication year - 2008
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.20831
Subject(s) - medicine , primitive neuroectodermal tumor , cd99 , ewing's sarcoma , nephrectomy , sarcoma , clear cell sarcoma , abdomen , histology , enolase , abdominal mass , pathology , wilms' tumor , kidney , abdominal pain , radiology , immunohistochemistry , vimentin
Abstract A 6‐year‐old female was admitted with abdominal pain and a mass in the right abdomen. Her lactose dehydrogenase level was 1,200 IU/L, and neuron specific enolase was 120 ng/ml. Computed tomography scan confirmed a large right renal mass with necrosis. A right radical nephrectomy was performed. The tumor was completely encapsulated. Based on small round cell histology, strong MIC‐2 (CD99) positive tumor cells, and EWS‐FLI‐1 fusion transcript, Ewing sarcoma/primitive neuroectodermal tumor of the kidney was diagnosed. Induction and follow‐up with seven cycles of chemotherapy were given after surgery. She has had no evidence of recurrence 90 months from diagnosis. Pediatr Blood Cancer 2008;50:180–183. © 2006 Wiley‐Liss, Inc.