Precursor B lymphoblastic leukemia 32 months after local therapy for a primary extramedullary myeloid cell tumor | Zendy

Szinnai Gabor | Zendy; Cogliatti Sergio B. | Zendy; Avoledo Pierino | Zendy; Dirnhofer Stephan | Zendy; Schmid Ulrico | Zendy; Kühne Thomas | Zendy

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Precursor B lymphoblastic leukemia 32 months after local therapy for a primary extramedullary myeloid cell tumor

Author(s) -

Szinnai Gabor,

Cogliatti Sergio B.,

Avoledo Pierino,

Dirnhofer Stephan,

Schmid Ulrico,

Kühne Thomas

Publication year - 2007

Publication title -

pediatric blood and cancer

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.116

H-Index - 105

eISSN - 1545-5017

pISSN - 1545-5009

DOI - 10.1002/pbc.20789

Subject(s) - medicine , lymphoblastic leukemia , myeloid leukemia , cancer research , myeloid , primary (astronomy) , leukemia , oncology , physics , astronomy

A primary extramedullary myeloid cell tumor (pEMT) of an inguinal lymph node was completely excised without subsequent anti‐tumor therapy in a 6‐year‐old child. Clinical observation and monitoring of blood and bone marrow (BM) did not reveal any pathologic results before 32 months, when a precursor B lymphoblastic leukemia was diagnosed. Identical T‐cell receptor gamma rearrangement in nodal pEMT and in precursor B lymphoblastic leukemia in BM indicates a clonal relationship of these two tumors. Pediatr Blood Cancer 2007;49:1039–1046. © 2006 Wiley‐Liss, Inc.

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