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The role of Helicobacter pylori infection in children with acute immune thrombocytopenic purpura
Author(s) -
Jaing TangHer,
Tsay PeiKwei,
Hung IouJih,
Chiu ChengHsun,
Yang ChaoPing,
Huang IAnne
Publication year - 2006
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.20577
Subject(s) - medicine , thrombocytopenic purpura , helicobacter pylori , helicobacter pylori infection , immune system , prospective cohort study , immunology , platelet , purpura (gastropod) , immune thrombocytopenia , cohort , gastroenterology , ecology , biology
The outcome of immune thrombocytopenic purpura (ITP) is classified as acute or chronic depending on whether platelet count returns to normal. The prevalence of Helicobacter pylori infection increases with age and is independent of gender. We investigated the prevalence of H. pylori infection in Chinese children from Northern Taiwan and analyzed the association between H. pylori infection and acute ITP. Our prospective cohort studies found no statistically significant relation between H. pylori infection and acute ITP. There is therefore no indication to screen children with presumed acute ITP for H. pylori infection. © 2005 Wiley‐Liss, Inc.