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Intraspinal and intracranial hemorrhage after lumbar puncture
Author(s) -
Lee Anselm C.W.,
Lau Yu,
Li C.H.,
Wong Y.C.,
Chiang Alan K.S.
Publication year - 2007
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.20551
Subject(s) - medicine , asymptomatic , lumbar puncture , surgery , hematoma , chemotherapy , neurological deficit , lumbar , spinal puncture , lymphoma , anesthesia , cerebrospinal fluid
Two cases of spinal epidural hematoma and two cases of intracranial subdural hematoma after lumbar puncture (LP) are reported in children receiving chemotherapy for acute lymphoblastic leukemia and non‐Hodgkin lymphoma. The bleeding was asymptomatic but interfered with treatment in one case, and caused either severe backache or headache but no neurological deficit in the other three patients. The platelet counts were 8 and 46 × 10 9 /L in two patients and were normal in the other patients at the time of LP. All recovered without surgical treatment. There is an inherent, albeit uncommon, risk of bleeding into the central nervous system associated with LP in children with cancer and should be distinguished from postdural puncture headache (PDPH). Thrombocytopenia is not always an accompanying factor. Pediatr Blood Cancer 2007;48:233–237. © 2006 Wiley‐Liss, Inc.