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Successful treatment of the HIV‐associated Burkitt lymphoma in a three‐year‐old child
Author(s) -
Fedorova Alina,
Mlyavaya Tamara,
Alexeichik Alexei,
Busel Tatyana,
Petrovich Inna,
Aleinikova Olga
Publication year - 2006
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.20500
Subject(s) - medicine , chemotherapy , lymphoma , human immunodeficiency virus (hiv) , antiretroviral therapy , pediatrics , oncology , viral load , immunology
We report a case of successful treatment of advanced Burkitt lymphoma in a 3‐year‐old girl with congenitally acquired HIV infection. She was treated with intensive chemotherapy combined with highly active anti‐retroviral therapy (HAART). She had not received any anti‐retroviral therapy and had stage C3 HIV infection on admission. She was treated with modified BFM 90 and remission was achieved. Simultaneously with chemotherapy, HAART with three drugs was carried out, resulting in improvements in HIV parameters. Our report suggests chemotherapy combined with HAART is feasible in children and may favorably change the outcomes in pediatric patients with AIDS‐NHL. © 2005 Wiley‐Liss, Inc.