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Post‐transplant multiple myeloma in a pediatric renal transplant patient
Author(s) -
Tcheng Wendy Y.,
Said Jonathan,
Hall Theodore,
AlAkash Samhar,
Malogolowkin Marcio,
Feig Stephen A.
Publication year - 2006
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.20482
Subject(s) - medicine , immunosuppression , multiple myeloma , mononucleosis , lymphoma , lymphoproliferative disorders , complication , lymphoproliferative disease , renal transplant , bone marrow transplant , bone marrow , pathology , immunology , transplantation , bone marrow transplantation , virus
Post‐transplant lymphoproliferative disease (PTLD) is a well‐recognized complication of the intense immunosuppression required in solid organ and bone marrow transplant recipients. The clinical presentation is varied and can range from a benign infectious mononucleosis‐like syndrome to malignant lymphoma. PTLD manifesting as multiple myeloma occurs rarely. We report the unique occurrence of Epstein–Barr virus (EBV)‐associated post‐transplant multiple myeloma in a 16‐year‐old male. In contrast to previously described cases of PTLD‐myeloma type, this patient was very young, had a clear association with EBV, and an indolent clinical course. © 2005 Wiley‐Liss, Inc.
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