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Thymic carcinoma in children
Author(s) -
Yaris Nilgün,
Nas Yunus,
Cobanoglu Umit,
Yavuz Melek N.
Publication year - 2006
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.20468
Subject(s) - thymic carcinoma , medicine , anaplasia , thymoma , thymus neoplasm , pathology , carcinoma , respiratory distress , immunohistochemistry , radiation therapy , sarcomatoid carcinoma , radiology
Thymic epithelial neoplasms consist of thymomas, thymic carcinoids, and thymic carcinomas. Carcinomas are malignant tumors of the thymus characterized by obvious cytological anaplasia. They constitute only 4%–14% of thymic epithelial neoplams. Thymic carcinoma rarely occurs in children. Research in the English literature carried out for the present study revealed only 14 cases younger than 18 years‐of‐age. Here we have reported a 16‐year old girl who presented with respiratory distress due to huge anterior mediastinal mass. Histological and immunohistochemical studies confirmed lymphoepithelioma‐like thymic carcinoma. She received systemic chemotherapy and radiotherapy. However, she died within 15 months due to progressive disease. © 2005 Wiley‐Liss, Inc.