Premium
Helicobacter pylori as cause of gastrointestinal disease in children with hemato‐oncologic diseases
Author(s) -
Castagnola Elio,
Calvillo Michaela,
Gigliotti Anna Rita,
Fioredda Francesca,
Hanau Guia,
Caviglia Ilaria,
Lanino Edoardo,
Dufour Carlo
Publication year - 2006
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.20459
Subject(s) - medicine , helicobacter pylori , cancer , gastroenterology , disease , gastrointestinal cancer , bone marrow , colorectal cancer
After documentation of a case of life threatening Helicobacter pylori ( H. pylori ) gastric ulcer in an adolescent girl on treatment for acute lymphoblastic leukaemia, we started to systematically look for gastro‐intestinal symptoms due to H. pylori infection in our cancer patients at G. Gaslini Children's Hospital. During a period of 46 months, we observed 13 further cases of severe dyspepsia syndrome or gastro intestinal bleeding associated with presence of H. pylori faecal antigen. All patients recovered with appropriate therapy. H. pylori may represent a cause of severe gastrointestinal complications in children with cancer or following bone marrow transplant. © 2005 Wiley‐Liss, Inc.