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Anaplastic transformation from papillary thyroid carcinoma with increased serum CA19‐9
Author(s) -
Ogawa Masahiro,
Hori Hiroki,
Hirayama Masahiro,
Kobayashi Minako,
Shiraishi Taizou,
Watanabe Yuri,
Komada Yoshihiro
Publication year - 2005
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.20375
Subject(s) - medicine , anaplastic carcinoma , thyroid carcinoma , anaplastic thyroid cancer , thyroidectomy , thyroid , pathology , ca19 9 , tumor marker , carcinoma , metastasis , neck dissection , lymph node , oncology , gastroenterology , thyroid cancer , cancer , pancreatic cancer
A 24‐year‐old woman presented with anaplastic transformation from papillary thyroid carcinoma with increased serum CA19‐9. The patient had been diagnosed as having papillary thyroid carcinoma with lung metastasis at 11 years of age. She received a total thyroidectomy with cervical lymph node dissection followed by iodine‐131 ( 131 I) therapy over 12 years, but died due to sudden onset of rapid dissemination. Elevated serum CA19‐9 was detected in the terminal stage, and anaplastic transformation was confirmed by post‐mortem examination. Although there are few clinical reports suggesting a prognostic indicator for anaplastic thyroid carcinoma, CA19‐9 may be a useful serum marker for this tumor. Pediatr Blood Cancer 2005; 45:64–67. © 2005 Wiley‐Liss, Inc.