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Juvenile papillomatosis of the breast in a male infant with Noonan Syndrome, café au lait spots, and family history of breast carcinoma
Author(s) -
Pacilli Maurizio,
Sebire Neil James,
Thambapillai Elmo,
Pierro Agostino
Publication year - 2005
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.20323
Subject(s) - papillomatosis , medicine , family history , noonan syndrome , breast carcinoma , café au lait spot , carcinoma , dermatology , pediatrics , breast cancer , pathology , cancer , neurofibromatosis
Juvenile papillomatosis (JP) of the breast is a rare condition, usually affecting women under 30 years of age. Although this is considered a benign lesion, follow‐up is recommended for the patient and family since there is an association with a family history of breast carcinoma and increased risk of development of breast carcinoma. We report an infant with JP, Noonan syndrome (NS), café au lait spots, and family history of breast carcinoma. Seven previously reported cases of JP in males exist, two occurring in infants. The association between JP and NS has not been previously reported. © 2005 Wiley‐Liss, Inc.