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Pseudomonas aeruginosa infection: An uncommon cause of post‐renal obstruction following induction therapy for acute lymphoblastic leukemia
Author(s) -
Burghardt Karolina M.,
Leonard Michael,
Feber Janusz,
Halton Jacqueline,
Filler Guido
Publication year - 2006
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.20321
Subject(s) - medicine , ganciclovir , surgery , asymptomatic , cystoscopy , acute lymphocytic leukemia , pancytopenia , maintenance therapy , gastroenterology , lymphoblastic leukemia , urinary system , leukemia , chemotherapy , bone marrow , immunology , virus , human cytomegalovirus
A 14‐month‐old infant presented with gastroenteritis with febrile pancytopenia and was diagnosed with acute lymphocytic leukemia (ALL). Ten days post induction therapy, the patient developed hypertension that was ascribed to steroid therapy and treated with metoprolol and amlodipine. As leukocyte numbers began to recover the asymptomatic patient became anuric. Ultrasound showed echoic floating structures in the bladder. Following cystoscopy and retrograde pyelography examination, purulent debris was irrigated from the bladder and grew Pseudomonas aeruginosa. Ciprofloxacin therapy was initiated and renal function was restored within 2 days. The case highlights the potential for renal obstruction after neutropenia recovery in children undergoing induction therapy for ALL. Pediatr Blood Cancer 2006, 46:512–513. © 2005 Wiley‐Liss, Inc.