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Superior mediastinal syndrome with Rowland–Payne syndrome: An unusual presentation of cervico‐mediastinal neuroblastoma
Author(s) -
Kapoor Vishal,
Lodha Rakesh,
Agarwala Sandeep
Publication year - 2005
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.20198
Subject(s) - medicine , neuroblastoma , presentation (obstetrics) , palsy , surgery , pathology , genetics , alternative medicine , biology , cell culture
Abstract A 5‐month‐old boy presented with superior mediastinal syndrome due to a large, unresectable cervico‐mediastinal neuroblastoma. He had an unusual constellation of findings not previously reported in neuroblastoma: Horner syndrome, phrenic nerve palsy, and palsy of the ipsilateral recurrent laryngeal nerve. This constellation of findings in adult malignancies is termed the Rowland–Payne syndrome. The child required prolonged mechanical ventilation but responded to chemotherapy and is now free of tumor and completely recovered. © 2004 Wiley‐Liss, Inc.