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Teratocarcinosarcoma of the oral cavity
Author(s) -
Crazzolara Roman,
Puelacher Wolfgang,
Ninkovic Milomir,
Zelger Bettina,
Buchberger Wolfgang,
Meister Bernhard,
Zimmerhackl Lothar B.,
KleinFranke Andreas
Publication year - 2004
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.20139
Subject(s) - medicine , carcinosarcoma , oral cavity , neoplasm , chemotherapy , surgical resection , pathology , teratoma , radiology , surgery , carcinoma , dentistry
Abstract Teratocarcinosarcoma (TCS) is a very rare and aggressive neoplasm characterized by teratoma and carcinosarcoma components. The authors report on a case of TCS in the oral cavity of a child. Rapid growth and extensive local destruction were prominent features prior to treatment. Histologic examination revealed various tissue elements, such as epithelial, mesenchymal, and neuroectodermal components. Chemotherapy was effective in reducing tumor mass, followed by partial anterior mandibulectomy and reconstruction with composite microvascular tissue transfer. The approach allowed radical resection of the tumor and functional reconstruction with excellent aesthetic results. © 2004 Wiley‐Liss, Inc.