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Aggressive bladder carcinoma in a child
Author(s) -
Lezamadel Valle Pablo,
Jerkins Gerald R.,
Rao Bhaskar N.,
Santana Victor M.,
Fuller Christine,
Merchant Thomas E.
Publication year - 2004
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.20100
Subject(s) - medicine , cystectomy , presentation (obstetrics) , chemotherapy , radiation therapy , carcinoma , neoplasm , urinary bladder , pathology , bladder tumor , oncology , urology , bladder cancer , radiology , cancer
The brief report describes an unusual case of high grade bladder neoplasm with divergent differentiation in a 31 month‐old child. The presentation included hematuria with tissue fragments and the tumor was confined to the bladder. The tumor behaved aggressively despite radical cystectomy, chemotherapy with agents known to be effective against epithelial and mesenchymal tumors and radiation therapy. Although rare, most malignant bladder neoplasms in children are low grade and present in early stages. Sarcomatoid differentiation in the setting of high‐grade urothelial carcinoma portends a poor prognosis. © 2004 Wiley‐Liss, Inc.