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Concurrent cystic mediastinal lymphangioma and paratesticular rhabdomyosarcoma
Author(s) -
Emir Suna,
Uǧur Handan,
Koloǧlu Meltem,
Erekul Selim,
Ünal Emel,
Taçyildiz Nurdan,
Yavuz Gülsan
Publication year - 2004
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.20081
Subject(s) - rhabdomyosarcoma , lymphangioma , medicine , sarcoma , pathology
The current report describes a 23‐month‐old boy with paratesticular rhabdomyosarcoma who was incidentally diagnosed as also having an isolated mediastinal cystic lymphangioma. The association of childhood rhabdomyosarcoma with various congenital anomalies and genetic alterations such as p53 mutations have been well known. However, mediastinal cystic lymphangioma has not been reported among the congenital anomalies diagnosed in rhabdomyosarcoma. Both rhabdomyosarcoma and lymphangioma originate from mesenchymal cells. This association may be coincidental or may point to a common genetic and/or developmental disorder of the mesencymal tissue. © 2004 Wiley‐Liss, Inc.