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Technical Aspects in Cerebrospinal Irradiation
Author(s) -
Bernier Valérie
Publication year - 2004
Publication title -
pediatric blood and cancer
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.116
H-Index - 105
eISSN - 1545-5017
pISSN - 1545-5009
DOI - 10.1002/pbc.10468
Subject(s) - medicine , cerebrospinal fluid , irradiation , pathology , nuclear physics , physics
Background Craniospinal irradiation (CSI) is commonly used for medulloblastoma patients and some others; for example, those with ependymoma. It is a complex technique where accuracy of field placement and choice of irradiation source and energy can play a major role in determining success or failure. Procedure A literature review of the techniques used and reported by treatment centers was undertaken. Results Great variability was found in methods and practices. This is striking because many hospitals treat fewer than five patients per year. Conclusion Standardized techniques with strict central review for quality control before therapy is initiated should become the norm. Standardization is especially important when clinical trials are planned. Valid outcome data depend on CSI uniformity. © 2004 Wiley‐Liss, Inc.