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The Journal of Pathology 2008 Jeremy Jass Prize for Research Excellence in Pathology
Author(s) -
Hall Peter A,
Poulsom Richard,
Coates Philip J,
Du MingQing,
Hogendoorn Pancras CW,
Jones Louise J,
Ladanyi Marc,
Murray Graeme I,
Niedobitek Gerald
Publication year - 2009
Publication title -
the journal of pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.964
H-Index - 184
eISSN - 1096-9896
pISSN - 0022-3417
DOI - 10.1002/path.2634
Subject(s) - epigenetics , excellence , gene silencing , microrna , molecular pathology , breast cancer , pathology , biology , medicine , cancer , gene , genetics , philosophy , epistemology
The first Jass Prize for Research Excellence has been awarded to a group from Hannover in Germany. These authors discovered the epigenetic inactivation of microRNA gene hsa‐mir‐9‐1 in human breast cancer and characterized its biological and clinical relevance. This frequent epigenetic silencing was found to occur early in the development of breast cancer, and illustrates another mechanism by which tumour development is influenced by genes that operate without expression as proteins. Copyright © 2009 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.