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High endothelial venules in B‐cell non‐Hodgkin malignant lymphomas
Author(s) -
Pajor Katalin,
Pap Tihamér,
Csanaky György,
Kalász Veronika
Publication year - 1990
Publication title -
the journal of pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.964
H-Index - 184
eISSN - 1096-9896
pISSN - 0022-3417
DOI - 10.1002/path.1711610213
Subject(s) - high endothelial venules , pathology , medicine , b cell , lymphatic system , immunology , antibody
The number of high endothelial venules (HEVs) per unit area was determined in 55 B‐cell non‐Hodgkin malignant lymphomas (nHMLs) classified according to the Kiel classification. The number of HEVs per unit area was significantly different between low‐ and high‐grade B‐cell nHMLs. In the low‐grade group, a large number of HEVs with preserved structure were present, whereas in high‐grade tumours the HEVs appeared damaged. The present findings support the previous observation attributing prognostic relevance to lymphocyte recirculation in nHMLs.