A non‐parametric grading system for intestinal metaplasia: Correlations with gastric tissue enzymes | Zendy

Finch P. J. | Zendy; Fallowfield M. E. | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

A non‐parametric grading system for intestinal metaplasia: Correlations with gastric tissue enzymes

Author(s) -

Finch P. J.,

Fallowfield M. E.

Publication year - 1989

Publication title -

the journal of pathology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.964

H-Index - 184

eISSN - 1096-9896

pISSN - 0022-3417

DOI - 10.1002/path.1711580406

Subject(s) - intestinal metaplasia , grading (engineering) , kappa , metaplasia , pathology , lactic dehydrogenase , gastroenterology , enzyme , medicine , chemistry , biology , stomach , biochemistry , mathematics , ecology , geometry

A novel method for grading intestinal metaplasia, with general applicability, is described. Highly significant agreement was found by kappa analysis both for intra‐observer ( k =0.90) and for inter‐observer ( k =0.85) variation, confirming the reproducibility of the method. The ranks derived by this method were correlated with gastric tissue levels of the enzymes beta‐glucuronidase, lactic dehydrogenase (LDH), and %m‐LDH. A significant ( P <0.05) positive correlation was found between intestinal metaplasia and %m‐LDH, but there was no correlation between intestinal metaplasia and beta‐glucuronidase or LDH.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research