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The pathology of diabetic hepatitis
Author(s) -
Nagore Norma,
Scheuer Peter J.
Publication year - 1988
Publication title -
the journal of pathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.964
H-Index - 184
eISSN - 1096-9896
pISSN - 0022-3417
DOI - 10.1002/path.1711560210
Subject(s) - alcoholic hepatitis , medicine , pathology , hepatitis , cirrhosis , diabetes mellitus , fatty liver , liver biopsy , lesion , biopsy , gastroenterology , alcoholic liver disease , disease , endocrinology
Liver biopsies from nine patients with maturity‐onset diabetes and fatty liver hepatitis were semiquantitively assessed, and the findings compared with those in alcoholic hepatitis. Overall appearances were similar, but the lesion in some diabetics was periportal rather than perivenular in location, and nuclear vacuolation of hepatocyte nuclei was alway present. The inflammatory infiltrate often included neutrophil leucocytes, as in the alcoholic. In three patients with multiple biopsies, progression appeared to be slow, but one patient developed cirrhosis.